Prompt used for this figure
Vertical research flowchart for a two-centre prospective device study with a historical control group, drawn as two parallel columns that merge at the bottom. Left column, prospective cohort (blue header): 1. Patients scheduled for surgery at two centres; 2. Preoperative imaging and clinical assessment; 3. Anatomical measurement and phenotype classification; 4. Virtual sizing of the new implant against two reference implants in the same patient; decision diamond "Safe implantation confirmed?": No leads to a grey dashed box "Screening failure, logged separately"; Yes leads to 5. Surgical plan; 6. Implantation at two centres; decision diamond "Safe intraoperatively?": No leads to "Intraoperative conversion, logged separately"; Yes leads to 7. Intraoperative fit recorded; 8. Blinded central radiographic review; 9. Fit score (grade A ≥ 85, B 70 to 84, C < 70); 10. Follow-up at 6 weeks, 3, 6 and 12 months. Right column, historical controls (green header): 1. Cases from the previous 3 to 5 years at both centres; 2. Screened for complete records; 3. At least 160 eligible cases extracted; 4. Propensity-score matching 1:1 or 1:2 on age, sex, BMI, side and grade; 5. At least 80 matched controls; 6. Outcomes collected with the same definitions. Bottom, both columns flow into a red-headed box "Comparative analysis": virtual paired comparison, matched cohort comparison, association between fit grade and outcome, and an inter-rater reliability sub-study (20% of images re-read, ICC ≥ 0.80).