Guide

Quasi-Experimental Research Designs: Comparison Groups, Interrupted Time Series, and Design Diagrams

A quasi-experiment estimates the effect of a treatment when units are not assigned to it by chance. This page draws the comparison-group, interrupted time series, and combined designs, lists the usual threats, and works two examples written for the diagrams.

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What is a quasi-experiment, and when do you use one?

A quasi-experiment has a treatment and an outcome, and it lacks random assignment. The people, classrooms, wards, or cities were already grouped, or a rule other than chance decided who received the program. You use the design when a randomized trial is impossible, unethical, or already too late: a campus policy that one residence hall adopted, a checklist a single ward started on a known Monday, a scholarship that turns on a published score.

What you can still do is choose a comparison that makes the main threat visible, measure the differences you can see, and say which differences you cannot see. Statistical control — covariates, matching, a difference-in-differences contrast, a model of the pre-intervention series — is part of the analysis. It is not a substitute for the diagram. If the diagram hides who was treated and when, the model will not repair that.

The notation on this page is the public Campbell and Cook shorthand. O is an observation. X is the intervention. A blank in the same column means “no treatment at that time,” not a missing data cell. R would mark random assignment; you will not see R on the quasi-experimental rows.

How is a quasi-experiment different from a randomized experiment?

Randomized experimentQuasi-experiment
Who gets XChance (R)An intact group, a clock time, or a cutoff
What the control buys youIn expectation, unobserved differences balanceA contrast you can draw; balance is something you check, not something assignment gives you
What you add in analysisThe estimate the design was built forCovariates, matching, or a model of the series — and a sentence about what those cannot fix
What the figure must showArms after randomizationWho is observed, who receives X, and the time order
Reporting flow, if you need oneA CONSORT participant diagram, for a trialNot CONSORT. A design diagram, then a study-flow figure if the proposal asks for steps

Random assignment is the line. Everything else — pretests, statistics, a carefully chosen comparison campus — can make a quasi-experiment more credible. None of it turns the design into an experiment. Write “quasi-experimental” in the methods section when you did not assign by chance, including when you wish you had.

Three design diagrams

The three figures in this section are the ones to learn first. Later sections add regression discontinuity and a staggered series, and a catalog table. The examples that follow use the same shapes with made-up series, labeled as illustrations.

Nonequivalent comparison group, pretest and posttest

Two intact groups. Both are measured before and after. Only one receives X. In symbols: O1 X O2 over O1 O2. “Nonequivalent” is the warning in the name: the groups were not formed by chance, so O1 is where you look for selection.

Interrupted time series

One unit, many observations, a sharp X. In symbols: O1 O2 O3 O4 X O5 O6 O7 O8. You need the stretch before X so you can see the level and the slope you are interrupting. A two-point before/after on a single group is not this design.

Interrupted time series with a comparison group

The same clock, two series, X in only one. A break that appears in both series at the same moment is a reason to suspect history (something else happened that week) rather than the program.

Nonequivalent comparison group, pretest and posttest

Hall A (program)

  1. OO1
  2. Xquiet-hours rule
  3. OO2

Hall B (comparison)

  1. OO1
  2. OO2

time →

O is an observation. X is the program. The second row never receives X. The groups already existed, so the two O1 cells are not interchangeable.

Interrupted time series

One unit

  1. OO1
  2. OO2
  3. OO3
  4. OO4
  5. Xchecklist starts
  6. OO5
  7. OO6
  8. OO7
  9. OO8

time →

Several observations before X and several after. A single jump from O4 to O5 is not enough to read; the shape of the series on each side of X is the design.

Interrupted time series plus a comparison series

Unit that changes

  1. OO1
  2. OO2
  3. OO3
  4. OO4
  5. XX
  6. OO5
  7. OO6
  8. OO7
  9. OO8

Comparison unit

  1. OO1
  2. OO2
  3. OO3
  4. OO4
  5. OO5
  6. OO6
  7. OO7
  8. OO8

time →

The comparison series is observed on the same clock and does not get X. A shock that hits both series at the same week is history, and it shows up as a break in both rows.

Threats to validity, and where they show on the diagram

The names below are the standard internal-validity threats used in the Campbell and Cook tradition, plus contamination, which is the usual external leak between groups. Each line says what to circle on the design diagram before you trust a drop or a rise.

ThreatWhat it meansWhat to look for on the diagram
HistorySome other event landed at the same time as XA second mark you could draw between the last pre O and the first post O; on an ITS-plus-comparison figure, a break in the untreated series too
MaturationThe unit was already changingA slope in the pre-X observations that already points at the “effect”
Regression to the meanAn extreme pretest drifts backA treated group whose O1 sits far from the comparison group’s O1
SelectionThe groups differed before XTwo O1 cells that you are not entitled to treat as the same population
Mortality (attrition)Different people remain at the posttestAn O2 that is no longer the O1 sample; the diagram should say who left
TestingThe pretest changed the posttestAn O1 that itself could train, fatigue, or alert the people you measure
InstrumentationThe measure changed at XA new form, rater, or device drawn on the same vertical line as X
ContaminationThe comparison group received some of XA dashed leak from the treated row into the untreated row

External validity is a separate question: would the same X do this in another hall, ward, or city? A clean diagram of one campus does not answer it. Say where you would not generalize, in a sentence next to the figure.

Design catalog

DesignNotationUse it whenMain threat to name
Nonequivalent comparison group, pretest–posttestO1 X O2 / O1 O2Two intact groups, one program, a measure on both sidesSelection
Interrupted time seriesO1 … O4 X O5 … O8One unit, many equally spaced observations, a sharp startHistory, instrumentation
ITS with a comparison seriesTwo of the ITS rows; X in oneA similar unit shares the calendar and not the programA shared shock (history)
Multiple interrupted time seriesSeveral series, X at different timesThe program rolls out on a staggerA cause that follows each site’s own start date
Regression discontinuityObservations ordered by a score, X on one side of a cutoffAssignment is a published thresholdManipulation of the score; a curve that is really a curve, not a jump

The regression-discontinuity sketch and the short selection list under the table are schematic. They are there so a proposal can pick a figure type before anyone estimates a model.

Multiple time series is the ITS-plus-comparison idea repeated: if X starts in March in one ward, June in a second, and October in a third, a cause that is “the program” should move with those dates. A cause that is “the new electronic record in April” will not line up with every start.

Regression discontinuity, schematic
cutoffscore

Assignment follows a score cutoff. Dots are a sketch of the idea, not observations from a study. The comparison that matters is just below the cutoff against just above it.

Which design diagram to draw
  1. Can you assign by chance? If yes, draw a randomized experiment and, when you report participants, a CONSORT flow — not this page.
  2. If assignment is a published score cutoff, draw a regression discontinuity.
  3. If one unit is observed many times around a sharp change, draw an interrupted time series. Add a comparison series when a similar unit does not change.
  4. If you have two intact groups and a pretest, draw the nonequivalent comparison diagram and name selection.

A selection sketch for a proposal meeting. It does not replace a power analysis or a registry entry.

Two examples written for this page

The counts below are illustrations invented for the diagrams. They are not results of a study, not administrative data, and not taken from any lecture handout. Round numbers are a teaching device. Do not cite them as findings.

Example 1 — nonequivalent comparison group

A university lets Residence Hall A adopt a weekday quiet-hours rule in week 6. Hall B, across the quad, does not. The outcome is noise complaints logged by student staff on one unchanged form. Students chose their halls. Nobody randomized the rule.

Weekly complaints, weeks 3–5 then weeks 6–8:

HallBefore (three weeks)RuleAfter (three weeks)
A18, 16, 17X in week 69, 8, 10
B14, 15, 13none13, 12, 14

This is O1 X O2 over O1 O2, with three pretest weeks collapsed into the “before” description so the table stays readable. The design diagram is the comparison-group figure above. Selection is the threat to write in the proposal: Hall A may have been the hall that wanted quiet hours. A regression to the mean story is weaker here because Hall A’s pretest is only a little higher than Hall B’s, but you still show both O1 series. Do not describe this as a randomized dorm trial.

Example 2 — interrupted time series, then the same series with a comparison

A hospital ward starts a handoff checklist in month 5. The outcome is medication-order clarifications per month, same definition all year.

Illustrative counts: 22, 24, 21, 23, then the checklist, then 14, 13, 15, 12.

That is O1 O2 O3 O4 X O5 O6 O7 O8. The pre-checklist months are flat, which makes maturation a less natural story than a level shift — in this invented series. Instrumentation still matters: if the clarification log changed in month 5, the diagram needs a second mark on X.

Add a comparison ward that never starts the checklist and stays near 19, 20, 18, 21, 20, 19, 21, 18. That is the third figure. If both wards drop in month 5, look for a hospital-wide event before you credit the checklist.

A third shape, only as a pointer: a department awards a research stipend to every applicant whose entrance score is at least 80, and you compare later course completion for students just under 80 and just over 80. That is regression discontinuity. There is no numeric table, because the figure is the cutoff, not a league table of scores.

Where this stops and a reporting flowchart starts

A design diagram shows assignment and time: who received X, who was observed, and in what order. A reporting flow shows how many units moved through a fixed report template.

A CONSORT flow diagram reports screening, randomization, allocation, follow-up, and analysis for a randomized trial. A PRISMA flow diagram reports how records were identified, screened, and included in a review. Neither figure is a quasi-experimental design diagram. Reporting flow is not the design.

If the study is quasi-experimental, draw the O/X diagram from this page first. If a proposal also wants the operational steps — recruitment, consent, the checklist, the analysis file — sketch that sequence in the research flowchart maker. The flowchart can say “nonequivalent halls” or “interrupted time series” in a box. It does not replace the design notation, and this guide does not replace the flowchart when you need a methods figure of the work itself.

Do not force quasi-experimental counts into a CONSORT template. CONSORT’s randomized-arm structure will invent a randomization you did not do.

Sources and attribution

This page is a Vizcept rewrite, not a reprint. Design names (nonequivalent control or comparison group, interrupted time series, regression discontinuity) are used in the public sense of the Campbell and Cook tradition. The examples, the counts, and the sentences are original to this page.

A set of public lecture notes for PPA 696 at California State University, Long Beach, formerly at http://www.csulb.edu/~msaintg/ppa696/696quasi.htm, is the page many methods reading lists still link. Those notes are thanked here as a widely cited teaching source. This guide does not reproduce their tables, assignments, or wording.

Archived copy, early 2012 snapshot via the Wayback Machine:

web.archive.org — CSULB PPA 696 quasi-experimental notes

Standard textbook treatments of the same designs remain the right citation for a thesis methods section. Point the archive link at the lecture notes; point this URL at the diagrams.

Questions about these designs

Is a pretest–posttest on one group a quasi-experiment?

A single group measured twice, with X in between, is a very weak before/after. It is not the comparison-group design and it is not an interrupted time series unless you have a real run of observations on each side of X. Prefer a comparison group or a series, and name history and maturation if you cannot.

Can I put these counts in a paper?

No. The hall and ward numbers on this page are invented so the diagrams have something to point at. Replace them with your own series, or omit numbers until you have them.

Should a quasi-experiment use a CONSORT or PRISMA figure?

No. CONSORT reports a randomized trial’s participants. PRISMA reports a review’s records. A quasi-experimental study needs a design diagram of O and X. Use the CONSORT or PRISMA tools only for those reporting figures.

Sketch your study flow

When the design diagram is chosen, describe the steps in order and generate a research flowchart for the proposal. Keep the O/X figure beside it so assignment and time stay visible.

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